Their state governor, Willie Obiano, sponsored the girls, Promise Nnalue, Jessica Osita, Nwabuaku Ossai, Adaeze Onuigbo and Vivian Okoye.
The team, led by Uchenna Onwuamaegbu Ugwu defeated representatives of other technological giants including the USA, Spain, Turkey, Uzbekistan and China to clinch the gold medal.
The team won the Challenge with a mobile application called the FD-Detector, which they developed to help tackle the Challenge of fake pharmaceutical products in Nigeria having spent five months researching and developing FD-Detector that swept through over 2000 competing applications to get to the finals in San Francisco.
Technovation is a programme that offers girls around the world the opportunity to learn the programming skills they need to emerge as tech-entrepreneurs and leaders.
Every year, girls are invited to identify a problem in their communities and then are challenged to solve them by developing Andriod applications that would address those problems.
115 countries participated in the qualifiers but only 12 teams from all over the world were selected as finalists for the pitch in Silicon Valley.